8
18
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11279 |
FGFR1/DDR2 inhibitor 1
|
Discoidin Domain Receptor (DDR); FGFR; Others | Angiogenesis; Others; Tyrosine Kinase/Adaptors |
FGFR1/DDR2 inhibitor 1 是一种具有口服活性的成纤维细胞生长因子受体 1 和盘状蛋白域受体 2 的抑制剂,能够抑制 FGFR1 (IC50:31.1 nM) 和 DDR2 (IC50:3.2 nM),具有抗肿瘤作用。 | |||
T39992 |
FGFR1 inhibitor-2
FGFR1 inhibitor-2 |
||
FGFR1 inhibitor-2 (with an IC50 of 4.55 μM in MDA-MB-231 cells) is a potent inhibitor of FGFR1. It is specifically useful for studying metastatic triple-negative breast cancer. | |||
T78830 |
FGFR1 inhibitor 7
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR1 inhibitor7(compound 5),作为一种FGFR1络氨酸激酶抑制剂,具有0.33 nM的IC50。它对多种人癌细胞系显示出广谱的细胞毒性,能在2.1 μM的IC50抑制MOLT3细胞系。 | |||
T78832 |
FGFR1 inhibitor-9
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR1inhibitor-9(Compound 9),一种FGFR1抑制剂(IC50为0.85 nM),可与FGFR1的ATP结合袋发生结合,并展现出抗癌活性。 | |||
T63816 | FGFR1 inhibitor-6 | ||
FGFR1 inhibitor-6 是 FGFR1 的有效抑制剂 (IC50: 16.31 nM),具有细胞毒活性。FGFR1 inhibitor-6 能够将细胞周期阻滞在前 G1 和 G2/M 期并诱导细胞凋亡 (apoptosis) 。 | |||
T79686 | FGFR1 inhibitor-10 | FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR1inhibitor-10 (Compound 4i)为一种选择性的FGFR1抑制剂,其IC50值为28 nM。该化合物有效阻断FGFR1磷酸化,并展现出了明显的抗血管生成和抗侵袭特性,具有潜在的抗肿瘤效果。 | |||
T78845 |
FGFR1/VEGFR2-IN-1
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR1/VEGFR2-IN-1 (compound 2b) 为FGFR1/VEGFR2抑制剂,适用于癌症研究。 | |||
T78831 |
FGFR1 inhibitor-8
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR1inhibitor-8(化合物9)是一种高效的FGFR1抑制剂,其IC50s为0.5 nM,能够与FGFR1的ATP结合口袋发生相互作用,并显示出抗癌活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06036 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
FGFR-1,FLG,CD331,HH2,FLT2,KAL2,FG... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7. | |||
TMPK-00393 |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR1 α,FGFR1 a... |
Human | HEK293 Cells |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7. | |||
TMPK-00395 |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGF R1a,FGFR1 α,FGFR... |
Human | HEK293 Cells |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7. | |||
TMPY-01011 |
FGFR1 Protein, Human, Recombinant (His)
KAL2,FLT2,FGFBR,HRTFDS,OGD,FLG,HBGFR,bFGF-R-1,CD33<... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4. | |||
TMPY-06034 |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
FLG,CD331,N-SAM,HBGFR,HRTFDS,BFGFR,OGD,KAL... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.8 kDa and the accession number is H9FRD4. | |||
TMPY-06035 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,CD331,BFGFR |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7. | |||
TMPY-03350 |
FGFR1 Protein, Rhesus, Recombinant (hFc)
fibroblast growth factor receptor 1 |
Rhesus | HEK293 Cells |
FGFR1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.2 kDa and the accession number is H9FRD4. | |||
TMPY-01781 |
FGFR1 Protein, Mouse, Recombinant (His)
Flt-2,FLG,fibroblast growth factor receptor 1,bFGF-... |
Mouse | HEK293 Cells |
FGFR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.9 kDa and the accession number is P16092-1. | |||
TMPY-01782 |
FGFR1 Protein, Mouse, Recombinant (hFc)
Hspy,fibroblast growth factor receptor 1,bFGF-R- |
Mouse | HEK293 Cells |
FGFR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.5 kDa and the accession number is P16092-1. | |||
TMPH-01337 |
FGFR1 Protein, Human, Recombinant (Yeast, His)
|
Human | P. pastoris (Yeast) |
FGFR1 Protein, Human, Recombinant (Yeast, His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 41.4 kDa and the accession number is P11362. | |||
TMPY-03926 |
FGFR1 Protein, Rhesus, Recombinant (His)
fibroblast growth factor receptor 1 |
Rhesus | HEK293 Cells |
FGFR1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is H9FRD4. | |||
TMPY-05777 |
FGFR1 Protein, Human, Recombinant (hFc)
N-SAM,OGD,HH2,HBGFR,FLT2,CEK,FLG,FGFR-1,FG... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.15 kDa and the accession number is NP_001341297.1. | |||
TMPY-06033 |
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
HBGFR,BFGFR,bFGF-R-1,FLG,FGFR- |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the accession number is H9FRD4. | |||
TMPY-05761 |
FGFR1 Protein, Human, Recombinant (His), Biotinylated
FLT-2,KAL2,FGFBR,HRTFDS,BFGFR,fibroblast growth fac... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4. | |||
TMPY-04371 |
FGFR1 Protein, Human, Recombinant (His & GST)
HRTFDS,CEK,OGD,FLG,FLT2,FGFBR,bFGF-R-1,N-SAM,fibrob... |
Human | Baculovirus Insect Cells |
FGFR1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the accession number is H9FRD4. | |||
TMPK-00392 |
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
CD331,FGFR-1,FLT-2,BFGFR... |
Human | HEK293 Cells |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession numb... | |||
TMPH-01336 |
FGFR1 Protein, Human, Recombinant (E. coli, His)
|
Human | E. coli |
FGFR1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 43.4 kDa and the accession number is P11362. | |||
TMPK-00394 |
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,... |
Human | HEK293 Cells |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the ... |